TY - JOUR
T1 - Increased erythrocyte aggregation in men with coronary artery disease and erectile dysfunction
AU - Justo, D.
AU - Mashav, N.
AU - Arbel, Y.
AU - Kinori, M.
AU - Steinvil, A.
AU - Swartzon, M.
AU - Molat, B.
AU - Halkin, A.
AU - Finkelstein, A.
AU - Heruti, R.
AU - Banai, S.
PY - 2009/5/30
Y1 - 2009/5/30
N2 - We studied the association between erythrocyte aggregation (EA) and erectile dysfunction (ED) in men with coronary artery disease (CAD). Men with CAD documented by coronary angiography filled the Sexual Health Inventory for Males questionnaire to detect ED and assess its severity. EA was evaluated by filming slides of blood smear. Low percentage of slide field covered by erythrocytes represented increased EA. Overall, 133 men with CAD, mean ages 62.4±12.2 years, were included: 100 (75.2%) with ED and 33 (24.8%) without ED. EA was increased among men with ED compared with men without ED (percentage of slide field covered by erythrocytes 66.7±14.7 vs 73.1±14.5%; P=0.03). After adjustment for age, diabetes mellitus, hemoglobin and hematocrit levels, EA was associated with ED severity (r=0.18; P=0.038).We conclude that EA is increased in men with CAD and ED. This finding may be relevant to the pathophysiology of ED in men with CAD.
AB - We studied the association between erythrocyte aggregation (EA) and erectile dysfunction (ED) in men with coronary artery disease (CAD). Men with CAD documented by coronary angiography filled the Sexual Health Inventory for Males questionnaire to detect ED and assess its severity. EA was evaluated by filming slides of blood smear. Low percentage of slide field covered by erythrocytes represented increased EA. Overall, 133 men with CAD, mean ages 62.4±12.2 years, were included: 100 (75.2%) with ED and 33 (24.8%) without ED. EA was increased among men with ED compared with men without ED (percentage of slide field covered by erythrocytes 66.7±14.7 vs 73.1±14.5%; P=0.03). After adjustment for age, diabetes mellitus, hemoglobin and hematocrit levels, EA was associated with ED severity (r=0.18; P=0.038).We conclude that EA is increased in men with CAD and ED. This finding may be relevant to the pathophysiology of ED in men with CAD.
KW - Coronary artery disease
KW - Erectile dysfunction
KW - Erythrocyte aggregation
UR - http://www.scopus.com/inward/record.url?scp=67649220666&partnerID=8YFLogxK
U2 - 10.1038/ijir.2009.6
DO - 10.1038/ijir.2009.6
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C2 - 19242480
AN - SCOPUS:67649220666
SN - 0955-9930
VL - 21
SP - 192
EP - 197
JO - International Journal of Impotence Research
JF - International Journal of Impotence Research
IS - 3
ER -
