In vivo reflectance confocal microscopy image interpretation for the dermatopathologist

Neda Shahriari, Jane M. Grant-Kels*, Harold Rabinovitz, Margaret Oliviero, Alon Scope

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review


Reflectance confocal microscopy (RCM) is a technology utilized for bedside diagnosis of cutaneous pathology by non-invasive, in vivo, cellular-level imaging. With the recent establishment of reimbursement codes by the US Centers for Medicaid and Medicare Services, RCM is now likely to be employed by clinical dermatologists and impact decision making on skin cancer management. Dermatopathologists, therefore, would benefit from learning how to interpret RCM images and how RCM findings correlate with histopathological criteria of diagnosis. This review briefly explains the principles behind RCM image acquisition, describes the key RCM features of normal skin, and delineates the RCM characteristics of frequently observed benign and malignant neoplasms.

Original languageEnglish
Pages (from-to)187-197
Number of pages11
JournalJournal of Cutaneous Pathology
Issue number3
StatePublished - Mar 2018


  • benign neoplasms
  • confocal microscopy
  • melanoma
  • nonmelanoma skin cancers


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