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In Vivo Imaging of the Coupling between Neuronal and CREB Activity in the Mouse Brain

  • Tal Laviv*
  • , Benjamin Scholl
  • , Paula Parra-Bueno
  • , Beth Foote
  • , Chuqiu Zhang
  • , Long Yan
  • , Yuki Hayano
  • , Jun Chu
  • , Ryohei Yasuda
  • *Corresponding author for this work
  • Max Planck Florida Institute for Neuroscience
  • Shenzhen Institute of Advanced Technology

Research output: Contribution to journal › Article › peer-review

51 Scopus citations

Abstract

Laviv et al. developed new biosensors that allow researchers to image plasticity-regulating activity of a transcription factor, CREB, in single cells in the brain of living mice.

Original languageEnglish
Pages (from-to)799-812.e5
JournalNeuron
Volume105
Issue number5
DOIs
StatePublished - 4 Mar 2020
Externally publishedYes

Funding

FundersFunder number
Florida Lifetime Imaging LLC
Human Frontiers Science Organization
Max Planck Florida Institute for Neuroscience
Shenzhen Science and Technology Innovation CommitteeJCYJ20170818164040422
National Institutes of HealthR01MH080047
National Institute of Neurological Disorders and StrokeDP1NS096787
Brain Research FoundationBRF-SlA-2018-01
Horowitz Foundation for Social Policy
National Natural Science Foundation of China31670872, 21874145
National Basic Research Program of China (973 Program)2017YFA0700403

    Keywords

    • CREB
    • FLIM
    • FRET
    • in vivo imaging

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