Abstract
Objective: To assess the reproductive potential in women ≥ 45 years of age. Design: Retrospective analysis. Setting: In vitro fertilization-embryo transfer unit, standard IVF and oocyte donation programs. Patients: One hundred twenty-seven patients ≥ 45 years old who applied for treatment of infertility. Intervention: Thirty-one patients underwent 52 treatment cycles in standard IVF. Ninety-six patients underwent 220 oocyte donation cycles. Results: Of the 52 standard IVF cycles, oocytes were retrieved successfully in only 32. Of these, fertilization and ET were performed in 21 cycles. None of these treatment cycles resulted in a clinical pregnancy. Of the 220 oocyte donation cycles, fertilization and ET were accomplished in 189 cycles. These resulted in 33 (17.5% per transfer) clinical pregnancies. Conclusions: These results suggest that oocyte donation may extend the reproductive potential in women ≥ 45 years old when little hope is offered by standard IVF.
Original language | English |
---|---|
Pages (from-to) | 71-76 |
Number of pages | 6 |
Journal | Fertility and Sterility |
Volume | 63 |
Issue number | 1 |
DOIs | |
State | Published - 1995 |
Externally published | Yes |
Keywords
- IVF
- aging
- endometrial receptivity
- oocyte donation