In vitro construction of cells-containing implants for articular cartilage regeneration

D. Robinson, M. Efrat, D. G. Mendes, N. Halperin, Z. Nevo

Research output: Contribution to journalArticlepeer-review

Abstract

Regeneration of destroyed articular cartilage can be induced by transplantation of cartilage cells into the defects. The best results are obtained by the use of either fetal allogeneic cells or autogenic ones. Induction of chondrogenesis in residual mesenchymal cells is optimal for obtaining large amounts of autogenic chondrocytes. Further modification of the technique is needed to reconstruct large defects. The cells are grown on biodegradable scaffolds and are later implanted into joint defects.

Original languageEnglish
Pages (from-to)231-235
Number of pages5
JournalAgents and Actions
Volume39
Issue numberSUPPL.
DOIs
StatePublished - 1993

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