In utero congestive heart failure due to maternal indomethacin treatment for polyhydramnios and premature labour in a fetus with antenatal closure of the foramen ovale

Reuwen Achiron, Shlomo Lipitz, Debora Kidron, Michael Berant, Julius Hegesh, Zeev Rotstein

Research output: Contribution to journalArticlepeer-review

Abstract

A case of severe fetal congestive heart failure due to occlusion of the ductus arteriosus in a mother treated with indomethacin for polyhydramnios and premature contractions is described. Closure of the fetal foramen ovale that escaped detection by prenatal echocardiography was later demonstrated at neonatal autopsy. This case suggests that indomethacin treatment in a ductus-dependent fetus may be hazardous. Therefore, careful surveillance of the fetus exposed to indomethacin in utero is warranted.

Original languageEnglish
Pages (from-to)652-656
Number of pages5
JournalPrenatal Diagnosis
Volume16
Issue number7
DOIs
StatePublished - Jul 1996

Keywords

  • Ductus arteriosus
  • Fetal heart failure
  • Foramen ovale
  • Maternal indomethacin

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