In utero congestive heart failure due to maternal indomethacin treatment for polyhydramnios and premature labour in a fetus with antenatal closure of the foramen ovale

Reuwen Achiron; Shlomo Lipitz; Debora Kidron; Michael Berant; Julius Hegesh; Zeev Rotstein

doi:10.1002/(SICI)1097-0223(199607)16:7<652::AID-PD917>3.0.CO;2-H

In utero congestive heart failure due to maternal indomethacin treatment for polyhydramnios and premature labour in a fetus with antenatal closure of the foramen ovale

Reuwen Achiron^*, Shlomo Lipitz, Debora Kidron, Michael Berant, Julius Hegesh, Zeev Rotstein

^*Corresponding author for this work

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14 Scopus citations

Abstract

A case of severe fetal congestive heart failure due to occlusion of the ductus arteriosus in a mother treated with indomethacin for polyhydramnios and premature contractions is described. Closure of the fetal foramen ovale that escaped detection by prenatal echocardiography was later demonstrated at neonatal autopsy. This case suggests that indomethacin treatment in a ductus-dependent fetus may be hazardous. Therefore, careful surveillance of the fetus exposed to indomethacin in utero is warranted.

Original language	English
Pages (from-to)	652-656
Number of pages	5
Journal	Prenatal Diagnosis
Volume	16
Issue number	7
DOIs	https://doi.org/10.1002/(SICI)1097-0223(199607)16:7<652::AID-PD917>3.0.CO;2-H
State	Published - Jul 1996

Keywords

Ductus arteriosus
Fetal heart failure
Foramen ovale
Maternal indomethacin

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10.1002/(SICI)1097-0223(199607)16:7<652::AID-PD917>3.0.CO;2-H

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title = "In utero congestive heart failure due to maternal indomethacin treatment for polyhydramnios and premature labour in a fetus with antenatal closure of the foramen ovale",

abstract = "A case of severe fetal congestive heart failure due to occlusion of the ductus arteriosus in a mother treated with indomethacin for polyhydramnios and premature contractions is described. Closure of the fetal foramen ovale that escaped detection by prenatal echocardiography was later demonstrated at neonatal autopsy. This case suggests that indomethacin treatment in a ductus-dependent fetus may be hazardous. Therefore, careful surveillance of the fetus exposed to indomethacin in utero is warranted.",

keywords = "Ductus arteriosus, Fetal heart failure, Foramen ovale, Maternal indomethacin",

author = "Reuwen Achiron and Shlomo Lipitz and Debora Kidron and Michael Berant and Julius Hegesh and Zeev Rotstein",

year = "1996",

month = jul,

doi = "10.1002/(SICI)1097-0223(199607)16:7<652::AID-PD917>3.0.CO;2-H",

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Achiron, R , Lipitz, S , Kidron, D, Berant, M, Hegesh, J & Rotstein, Z 1996, 'In utero congestive heart failure due to maternal indomethacin treatment for polyhydramnios and premature labour in a fetus with antenatal closure of the foramen ovale', Prenatal Diagnosis, vol. 16, no. 7, pp. 652-656. https://doi.org/10.1002/(SICI)1097-0223(199607)16:7<652::AID-PD917>3.0.CO;2-H

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AU - Berant, Michael

AU - Hegesh, Julius

AU - Rotstein, Zeev

PY - 1996/7

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N2 - A case of severe fetal congestive heart failure due to occlusion of the ductus arteriosus in a mother treated with indomethacin for polyhydramnios and premature contractions is described. Closure of the fetal foramen ovale that escaped detection by prenatal echocardiography was later demonstrated at neonatal autopsy. This case suggests that indomethacin treatment in a ductus-dependent fetus may be hazardous. Therefore, careful surveillance of the fetus exposed to indomethacin in utero is warranted.

AB - A case of severe fetal congestive heart failure due to occlusion of the ductus arteriosus in a mother treated with indomethacin for polyhydramnios and premature contractions is described. Closure of the fetal foramen ovale that escaped detection by prenatal echocardiography was later demonstrated at neonatal autopsy. This case suggests that indomethacin treatment in a ductus-dependent fetus may be hazardous. Therefore, careful surveillance of the fetus exposed to indomethacin in utero is warranted.

KW - Ductus arteriosus

KW - Fetal heart failure

KW - Foramen ovale

KW - Maternal indomethacin

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In utero congestive heart failure due to maternal indomethacin treatment for polyhydramnios and premature labour in a fetus with antenatal closure of the foramen ovale

Abstract

Keywords

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