In the Eye of the Storm: Bi-Directional Electrophysiological Investigation of the Intact Retina

Ieva Vėbraitė, Yael Hanein

Research output: Contribution to journalReview articlepeer-review

Abstract

Electrophysiological investigations reveal a great deal about the organization and function of the retina. In particular, investigations of explanted retinas with multi electrode arrays are widely used for basic and applied research purposes, offering high-resolution and detailed information about connectivity and structure. Low-resolution, non-invasive approaches are also widely used. Owing to its delicate nature, high-resolution electrophysiological investigations of the intact retina until now are sparse. In this Mini Review, we discuss progress, challenges and opportunities for electrode arrays suitable for high-resolution, multisite electrophysiological interfacing with the intact retina. In particular, existing gaps in achieving bi-directional electrophysiological investigation of the intact retina are discussed.

Original languageEnglish
Article number829323
JournalFrontiers in Neuroscience
Volume16
DOIs
StatePublished - 25 Feb 2022

Keywords

  • bi-directional electrophysiology
  • micro-electrodes
  • multi electrode arrays
  • neurostimulation
  • retina
  • soft neural interfaces

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