In-stent restenosis of drug-eluting stents

Sa'ar Minha, Augusto D. Pichard, Ron Waksman

Research output: Contribution to journalReview articlepeer-review


Drug-eluting stents (DES) have emerged as an improved alternative to bare-metal stents by demonstrating reduced rates of restenosis and target lesion revascularization. This emergence has led to the unrestricted use of DES for various indications and lesions, and subsequently revealed DES in-stent restenosis as a novel interventional therapeutic dilemma. Recent insights regarding the patho-physiological processes and therapeutic alternatives have added to the accumulated knowledge regarding the appropriate approach to this phenomenon. This review aims to detail the mechanism and clinical presentation of, and therapeutic strategies for, the treatment of DES in in-stent restenosis.

Original languageEnglish
Pages (from-to)721-731
Number of pages11
JournalFuture Cardiology
Issue number5
StatePublished - Sep 2013
Externally publishedYes


  • Bare metal stent
  • Drug-eluting stent
  • In-stent restenosis


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