Improving blood product management in placenta accreta patients with severe bleeding: institutional experience

A. Zabida*, G. Zahavi, J. Bartoszko, M. Otálora-Esteban, J. Weinstein, J. Frogel, L. Miller, E. Sivan, D. Orkin, I. Dolgoker, H. Berkenstadt

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review


Background: Placenta accrete spectrum (PAS) is a significant risk factor for postpartum hemorrhage and effective blood product management is critical in ensuring patient safety. In PAS patients undergoing cesarean section (CS) blood transfusion management guided by the combined clinical experience of the anesthesiologist and surgeon with point-of-care coagulation testing appears safe and effective. We describe and evaluate our experience and identify potential areas for improvement with blood product management in this patient population. Methods: A retrospective chart review of peri-operative demographic, anesthetic, and obstetric data was conducted for all patients with PAS undergoing CS between 2012 and 2018 at our center. To facilitate a practical evaluation of blood product management, we divided patients into two groups based on the severity of bleeding. Results: A total of 221 parturients with PAS underwent CS, with 133 in group 1 requiring excessive amounts of transfusion and 88 in group 2 requiring management similar to other uncomplicated CS cases. There were no deaths or instances of disseminated intravascular coagulation, and intensive care unit admission occurred in five cases (2.2%). Patients in group 1 had higher mean nadir values of intra-operative hemoglobin and platelet count. We observed a high rate of missing data for peri-operative measurement of lactate and fibrinogen, PAS grade documentation, and temperature monitoring. Conclusion: Given no significant morbidity or mortality, clinical judgment in experienced centers appears safe for the management of PAS patients undergoing CS. The adoption of an institutional protocol and point-of-care coagulation testing could decrease over-transfusion and associated complications.

Original languageEnglish
Article number103904
JournalInternational Journal of Obstetric Anesthesia
StatePublished - Nov 2023


  • Blood product management
  • Overtransfusion
  • Placenta accreta spectrum
  • Point of care coagulation testing
  • Quality improvement


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