Improved results in multifetal pregnancy reduction: A report of 72 cases

S. Lipitz*, Y. Yaron, J. Shalev, R. Achiron, M. Zolti, S. Mashiach

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

15 Scopus citations


Objective: To evaluate pregnancy outcome after either transabdominal or transvaginal multifetal pregnancy reduction. Design: A study of 72 consecutive multifetal pregnancy reductions. Setting: Department of Obstetrics and Gynecology, The Chaim Sheba Medical Center Tel Hashomer, Israel. Patients: Seventy-two patients with multifetal pregnancies: 2 twins, 27 triplets, 26 quadruplets, 10 quintuplets, 3 sextuplets, 1 septuplet, 2 nontuplets, and one pregnancy with 12 fetuses. Intervention: Multifetal pregnancy reduction was performed at 9 to 13 weeks' gestation by either transabdominal or transvaginal potassium chloride injection. Main Outcome Measures: Early and late complications related to the procedure, outcome of pregnancy, and comparison of two periods. Results: Procedures performed between 1984 and 1989 (36 patients) were associated with a 33.3% pregnancy loss, whereas those performed between 1990 and 1992 (36 patients) were associated with no pregnancy loss. Of the 17 patients with quintuplets or more, 10 (59%) delivered live and healthy newborns. No difference was found when comparing the transabdominal and the transvaginal approaches. Conclusions: Both transvaginal and transabdominal approaches are comparable. There is a remarkable decrease in pregnancy loss with experience.

Original languageEnglish
Pages (from-to)59-61
Number of pages3
JournalFertility and Sterility
Issue number1
StatePublished - 1994
Externally publishedYes


  • Multifetal pregnancy reduction
  • multiple pregnancy
  • ovulation induction


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