Impact of Gender and Age on In Vivo Virtual Histology-Intravascular Ultrasound Imaging Plaque Characterization (from the global Virtual Histology Intravascular Ultrasound [VH-IVUS] Registry)

Jie Qian, Akiko Maehara*, Gary S. Mintz, M. Pauliina Margolis, Amir Lerman, Jason Rogers, Shuel Banai, Samer Kazziha, Celia Castellanos, Lokesh Dani, Martin Fahy, Gregg W. Stone, Martin B. Leon

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

Abstract

Virtual histology intravascular ultrasound (VH-IVUS) analyses were performed in the first 990 patients enrolled in the 3,000+ patient global VH-IVUS Registry to assess the impact of gender and age on in vivo VH-IVUS plaque characterization. The 990 patients were divided into 3 age group terciles (<58, 58 to 68, and >68 years) and again divided according to gender. In conclusion, (1) both women and men had an increase in plaque with increasing age; (2) at any age, men had more plaque than women; (3) percentages of dense calcium and necrotic core increased with increasing patient age in both men and women; and (4) gender differences were lowest in the oldest tercile (>68 years).

Original languageEnglish
Pages (from-to)1210-1214
Number of pages5
JournalAmerican Journal of Cardiology
Volume103
Issue number9
DOIs
StatePublished - 1 May 2009
Externally publishedYes

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