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Immunosuppressive Activity of Rabbit Antisera Directed against Mouse Lymphocytic Leukemia L1210

  • Roswell Park Cancer Institute

Research output: Contribution to journalArticlepeer-review

4 Scopus citations

Abstract

Rabbit antisera directed against cultured mouse lymphocytic leukemia L1210 cells as well as those directed against the ascitis form were shown to be immunosuppressive when injected into mice prior to immunization with sheep erythrocytes. The extent of immunosuppression was comparable to the one induced by injection of antisera directed against mouse spleen and lymph node antigens. The degree of immunosupression was quantitated by assaying the number of antibody forming cells by plaque formation in a sheep erythrocyte medium, and by titration of humoral hemagglutinins.

Original languageEnglish
Pages (from-to)562-565
Number of pages4
JournalProceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N. Y.)
Volume127
Issue number2
DOIs
StatePublished - Feb 1968
Externally publishedYes

Funding

Funders
United States Atomic Energy Commission

    UN SDGs

    This output contributes to the following UN Sustainable Development Goals (SDGs)

    1. SDG 3 - Good Health and Well-being
      SDG 3 Good Health and Well-being

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