TY - JOUR
T1 - Immunosuppressive Activity of Rabbit Antisera Directed against Mouse Lymphocytic Leukemia L1210
AU - Witz, Isaac
AU - Yagi, Yasuo
AU - Pressman, David
N1 - Funding Information:
Supported in part by Contract #AT-(30-1) −2651 from the U. S. Atomic Energy Commission.
PY - 1968/2
Y1 - 1968/2
N2 - Rabbit antisera directed against cultured mouse lymphocytic leukemia L1210 cells as well as those directed against the ascitis form were shown to be immunosuppressive when injected into mice prior to immunization with sheep erythrocytes. The extent of immunosuppression was comparable to the one induced by injection of antisera directed against mouse spleen and lymph node antigens. The degree of immunosupression was quantitated by assaying the number of antibody forming cells by plaque formation in a sheep erythrocyte medium, and by titration of humoral hemagglutinins.
AB - Rabbit antisera directed against cultured mouse lymphocytic leukemia L1210 cells as well as those directed against the ascitis form were shown to be immunosuppressive when injected into mice prior to immunization with sheep erythrocytes. The extent of immunosuppression was comparable to the one induced by injection of antisera directed against mouse spleen and lymph node antigens. The degree of immunosupression was quantitated by assaying the number of antibody forming cells by plaque formation in a sheep erythrocyte medium, and by titration of humoral hemagglutinins.
UR - http://www.scopus.com/inward/record.url?scp=0014251939&partnerID=8YFLogxK
U2 - 10.3181/00379727-127-32741
DO - 10.3181/00379727-127-32741
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AN - SCOPUS:0014251939
SN - 0037-9727
VL - 127
SP - 562
EP - 565
JO - Experimental Biology and Medicine
JF - Experimental Biology and Medicine
IS - 2
ER -
