Abstract
Basal morning plasma levels of immunoreactive β-endorphin (ir-β-EP), cortisol, and growth hormone (GH) were assessed in 13 obsessive-compulsive disorder (OCD) patients in comparison to 20 healthy controls. All subjects were drug free for at least 1 year. The mean plasma level of ir-β-EP was significantly lower (36%) in the OCD patients when compared with the control subjects. The decrease in ir-β-EP was not accompanied by alteration in cortisol and GH plasma levels.
| Original language | English |
|---|---|
| Pages (from-to) | 297-302 |
| Number of pages | 6 |
| Journal | Clinical Neuropharmacology |
| Volume | 13 |
| Issue number | 4 |
| DOIs | |
| State | Published - 1990 |
| Externally published | Yes |
Keywords
- Cortisol
- Growth hormone
- Obsessive-compulsive disorder
- Stress
- β-Endorphin