Immunoreactive β-endorphin, cortisol, and growth hormone plasma levels in obsessive-compulsive disorder

R. Weizman, I. Gil-Ad, H. Hermesh, H. Munitz, Z. Laron

Research output: Contribution to journalArticlepeer-review

Abstract

Basal morning plasma levels of immunoreactive β-endorphin (ir-β-EP), cortisol, and growth hormone (GH) were assessed in 13 obsessive-compulsive disorder (OCD) patients in comparison to 20 healthy controls. All subjects were drug free for at least 1 year. The mean plasma level of ir-β-EP was significantly lower (36%) in the OCD patients when compared with the control subjects. The decrease in ir-β-EP was not accompanied by alteration in cortisol and GH plasma levels.

Original languageEnglish
Pages (from-to)297-302
Number of pages6
JournalClinical Neuropharmacology
Volume13
Issue number4
DOIs
StatePublished - 1990
Externally publishedYes

Keywords

  • Cortisol
  • Growth hormone
  • Obsessive-compulsive disorder
  • Stress
  • β-Endorphin

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