Immunologic studies on hamsters infected with entamoeba histolytica

D. Gold, L. G. Norman, S. E. Maddison, I. G. Kagan

Research output: Contribution to journalArticlepeer-review


The serologic and cell-mediated immune responses of hamsters exposed to 2 strains of Entamoeba hystolitica (HM-1 and HM-19) were evaluated by a series of in vitro tests. The pathogenicity of the 2 strains was evaluated in terms of their ability to produce liver abscesses and spleen enlargement. Antibody response was evaluated by the indirect hemagglutination test. The cellular immune response was assayed by increased DNA synthesis by lymphocytes and migration inhibition of macrophages.

Original languageEnglish
Pages (from-to)866-873
Number of pages8
JournalJournal of Parasitology
Issue number5
StatePublished - 1978
Externally publishedYes


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