TY - JOUR
T1 - Immediate tight sealing of skin incisions using an innovative temperature-controlled laser soldering device
T2 - In vivo study in porcine skin
AU - Simhon, David
AU - Halpern, Marisa
AU - Brosh, Tamar
AU - Vasilyev, Tamar
AU - Ravid, Avi
AU - Tennenbaum, Tamar
AU - Nevo, Zvi
AU - Katzir, Abraham
PY - 2007/2
Y1 - 2007/2
N2 - BACKGROUND: A feedback temperature-controlled laser soldering system (TCLS) was used for bonding skin incisions on the backs of pigs. The study was aimed: 1) to characterize the optimal soldering parameters, and 2) to compare the immediate and long-term wound healing outcomes with other wound closure modalities. MATERIALS AND METHODS: A TCLS was used to bond the approximated wound margins of skin incisions on porcine backs. The reparative outcomes were evaluated macroscopically, microscopically, and immunohistochemically. RESULTS: The optimal soldering temperature was found to be 65°C and the operating time was significantly shorter than with suturing. The immediate tight sealing of the wound by the TCLS contributed to rapid, high quality wound healing in comparison to Dermabond or Histoacryl cyanoacrylate glues or standard suturing. CONCLUSIONS: TCLS of incisions in porcine skin has numerous advantages, including rapid procedure and high quality reparative outcomes, over the common standard wound closure procedures. Further studies with a variety of skin lesions are needed before advocating this technique for clinical use.
AB - BACKGROUND: A feedback temperature-controlled laser soldering system (TCLS) was used for bonding skin incisions on the backs of pigs. The study was aimed: 1) to characterize the optimal soldering parameters, and 2) to compare the immediate and long-term wound healing outcomes with other wound closure modalities. MATERIALS AND METHODS: A TCLS was used to bond the approximated wound margins of skin incisions on porcine backs. The reparative outcomes were evaluated macroscopically, microscopically, and immunohistochemically. RESULTS: The optimal soldering temperature was found to be 65°C and the operating time was significantly shorter than with suturing. The immediate tight sealing of the wound by the TCLS contributed to rapid, high quality wound healing in comparison to Dermabond or Histoacryl cyanoacrylate glues or standard suturing. CONCLUSIONS: TCLS of incisions in porcine skin has numerous advantages, including rapid procedure and high quality reparative outcomes, over the common standard wound closure procedures. Further studies with a variety of skin lesions are needed before advocating this technique for clinical use.
UR - http://www.scopus.com/inward/record.url?scp=33846423540&partnerID=8YFLogxK
U2 - 10.1097/01.sla.0000232554.13719.10
DO - 10.1097/01.sla.0000232554.13719.10
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AN - SCOPUS:33846423540
SN - 0003-4932
VL - 245
SP - 206
EP - 213
JO - Annals of Surgery
JF - Annals of Surgery
IS - 2
ER -