Idiopathic non-obstructive hypertrophic cardiomyopathy, vitamin B12 deficiency and gastric adenocarcinoma: An unreported association in a teenager

B. Wolach, M. Rothschild, A. Pomeranz, A. Raz, M. Ben Arush, V. Rathaus, J. Bernheim, B. Novis, S. Katz

Research output: Contribution to journalArticlepeer-review

Abstract

A 14-year-old boy presented with anorexia and weakness whereon the diagnosis of dimorphic anaemia was made. An excellent response to iron and vitamin B12 was observed. In addition, the patient had non-obstructive hypertrophic cardiomyopathy. At endoscopy 2.5 years later, an adenocarcinoma was diagnosed and the patient underwent a high subtotal gastrectomy. To the best of our knowledge, this rare association has never been reported in children. Conclusion. We report a youngster with pernicious anaemia, associated with non-obstructive hypertrophic cardiomyopathy in whom gastric adenocarcinoma was found. Patients with pernicious anaemia are at greater risk of developing gastric carcinoma than the general population, therefore we recommend routine periodic gastroscopic surveillance in the paediatric population with pernicious anaemia.

Original languageEnglish
Pages (from-to)715-718
Number of pages4
JournalEuropean Journal of Pediatrics
Volume157
Issue number9
DOIs
StatePublished - 1998
Externally publishedYes

Keywords

  • Gastric adenocarcinoma
  • Non-obstructive hypertrophic cardiomyopathy
  • Vitamin B deficiency

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