Idiopathic heinz body hemolytic anemia in newborn infants

A. Ballin, E. J. Brown, A. Zipursky

Research output: Contribution to journalArticlepeer-review

Abstract

Heinz body hemolytic anemia developed in six full-term infants while at home during the first 2 weeks of life. The disorder first manifested as hyperbilirubinemia. However, in all cases, severe anemia (hemoglobin concentration 49-73 g/L) developed during the 4-12 days of hospitalization. The infants had not been exposed to known oxidants, and their erythrocytes were not glucose-6- phosphate dehydrogenase (G6PD) deficient and contained no unstable hemoglobin. It is hypothesized that in these newborn infants, Heinz body hemolytic anemia developed as a result of ingestion of an oxidant contained in feedings. The nature of this agent is as yet unknown.

Original languageEnglish
Pages (from-to)3-7
Number of pages5
JournalJournal of Pediatric Hematology/Oncology
Volume11
Issue number1
DOIs
StatePublished - 1989
Externally publishedYes

Keywords

  • Heinz body
  • Hemolytic anemia
  • Newborn

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