Identification of two distinct protein carboxyl methyltransferases in eucaryotic cells

Roya Solomon; Orit Katzir; Yaakov Egozi; Yoel Kloog

doi:10.1016/0014-5793(88)81045-7

Identification of two distinct protein carboxyl methyltransferases in eucaryotic cells

Roya Solomon, Orit Katzir, Yaakov Egozi, Yoel Kloog^*

^*Corresponding author for this work

Department of Neurobiology

Tel Aviv University

Research output: Contribution to journal › Article › peer-review

3 Scopus citations

Abstract

Two distinct protein carboxyl methyltransferases (PCM) were identified in the electric organ of Torpedo ocellata. They were separated from each other in the active form by means of nondenaturing gel electrophoresis and by p-(chloromercuri) benzoate-agarose chromatography, and were individually identified by specific polyclonal antibodies. The existence of at least two distinct PCMs in eucaryotic cells raises the possibility that these enzymes are involved in distinct transmethylation reactions.

Original language	English
Pages (from-to)	131-135
Number of pages	5
Journal	FEBS Letters
Volume	241
Issue number	1-2
DOIs	https://doi.org/10.1016/0014-5793(88)81045-7
State	Published - 5 Dec 1988

Keywords

Protein carboxyl methyltransferase
Protein methylation

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10.1016/0014-5793(88)81045-7

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abstract = "Two distinct protein carboxyl methyltransferases (PCM) were identified in the electric organ of Torpedo ocellata. They were separated from each other in the active form by means of nondenaturing gel electrophoresis and by p-(chloromercuri) benzoate-agarose chromatography, and were individually identified by specific polyclonal antibodies. The existence of at least two distinct PCMs in eucaryotic cells raises the possibility that these enzymes are involved in distinct transmethylation reactions.",

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AU - Egozi, Yaakov

AU - Kloog, Yoel

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AB - Two distinct protein carboxyl methyltransferases (PCM) were identified in the electric organ of Torpedo ocellata. They were separated from each other in the active form by means of nondenaturing gel electrophoresis and by p-(chloromercuri) benzoate-agarose chromatography, and were individually identified by specific polyclonal antibodies. The existence of at least two distinct PCMs in eucaryotic cells raises the possibility that these enzymes are involved in distinct transmethylation reactions.

KW - Protein carboxyl methyltransferase

KW - Protein methylation

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Identification of two distinct protein carboxyl methyltransferases in eucaryotic cells

Abstract

Keywords

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