@inproceedings{c2b5ad20436c421c9a1690c21e14346e,
title = "Identification of gender specific biomarkers for Alzheimer{\textquoteright}s disease",
abstract = "The paper presents experiments with a novel clustering methodology that enables identification of subpopulations of the Alzheimer{\textquoteright}s disease patients that are homogeneous in respect of both clinical and biological descriptors. It is expected that recognition of relevant connections between clinical and biological descriptors will be easier within such subpopulations. Our dataset includes 317 female and 342 male patients from the ADNI study that are described by a total of 243 biological and clinical descriptors recorded at baseline evaluation. The constructed clusters clearly demonstrate differences between female and male patient subpopulations. An interesting result is identification of a cluster of male Alzheimer{\textquoteright}s disease patients that are, surprisingly, characterized by increased intracerebral and whole brain volumes. The finding suggests existence of two different biological pathways for the Alzheimer{\textquoteright}s disease.",
author = "Dragan Gamberger and Bernard {\v Z}enko and Alexis Mitelpunkt and Nada Lavra{\v c} and {Alzheimer{\textquoteright}s Disease Neuroimaging Initiative}, {Disease Neuroimaging Initiative}",
note = "Publisher Copyright: {\textcopyright} Springer International Publishing Switzerland 2015.; 8th International Conference on Brain Informatics and Health, BIH 2015 ; Conference date: 30-08-2015 Through 02-09-2015",
year = "2015",
doi = "10.1007/978-3-319-23344-4_6",
language = "אנגלית",
isbn = "9783319233437",
series = "Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics)",
publisher = "Springer Verlag",
pages = "57--66",
editor = "{Guo Y.}, Yike and {Hill S.}, Sean and Karl Friston and Hanchuan Peng and {Faisal A.}, Aldo",
booktitle = "Brain Informatics and Health - 8th International Conference, BIH 2015, Proceedings",
}