Hypotensive reactions associated with transfusion of bedside leukocyte-reduction filtered blood products in heart transplanted patients

Jacob Lavee*, Yoav Paz

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

8 Scopus citations

Abstract

Severe hypotensive reactions that occur during transfusions of blood products to non-transplanted patients were recently linked to the use of bedside leukocyte-reduction filters, sometimes in association with angiotensin-converting enzyme (ACE) inhibitor treatment. We present the first report of such reactions in patients who underwent orthotopic heart transplantation. Fourteen (47%) of the 30 transfused patients experienced severe hypotensive reaction during filtered transfusion of at least 1 unit of blood product, with a total of 24 episodes. Eleven (79%) of these patients were treated pre-operatively with ACE inhibitors.

Original languageEnglish
Pages (from-to)759-761
Number of pages3
JournalJournal of Heart and Lung Transplantation
Volume20
Issue number7
DOIs
StatePublished - 2001
Externally publishedYes

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