Hypoglycemia-induced hemolysis in glucose-6-phosphate dehydrogenase deficiency

Oded Shalev*, Rami Eliakim, Gilles Z. Lugassy, Jacob Menczel

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review


We present a young man with Mediterranean type glucose-6-phosphate dehydrogenase (G6PD) deficiency and insulin-dependent diabetes mellitus whose brittle course was characterized by recurrent bouts of hypoglycemia and diabetic ketoacidosis (DKA). While neither of the episodes of DKA was complicated by hemolysis, hemolytic anemia consistently followed the recurrent attacks of hypoglycemia. Stringent control of the patient's blood glucose levels in the upper limit and slightly above the normal range successfully prevented recurrence of hypoglycemia and recrudescence of hemolytic anemia. Hypoglycemia is proposed as capable of inducing hemolysis in G6PD deficiency.

Original languageEnglish
Pages (from-to)227-229
Number of pages3
JournalActa Haematologica
Issue number4
StatePublished - 1985
Externally publishedYes


  • Glucose-6-phosphate dehydrogenase deficiency
  • Hemolysis
  • Hypoglycemia


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