Hyperthyroidism after Iodinated Contrast Medium

INORGANIC iodine administration can precipitate hyperthyroidism in susceptible patients.^1,2 The patient with an autonomous nodule of the thyroid described below appeared clinically euthyroid despite a slightly elevated serum tri-iodothyronine level, but became clinically hyperthyroid after administration of organic iodine in the course of intravenous pyelography. Case Report A 57-year-old woman was seen in 1969 because of a thyroid mass. ¹³¹I scan of the thyroid revealed uptake mainly by the mass in the right lobe. Thyroidal accumulation of radioiodine was 11 per cent in four hours (normal, less than 15 per cent), and 29 per cent in 24 hours (normal, 15.  . .