TY - JOUR
T1 - Hyperprolactinemia, galactorrhea and amenorrhea in women with a spinal cord injury
AU - Berezin, M.
AU - Ohry, A.
AU - Shemesh, Y.
AU - Zeilig, G.
AU - Brooks, M. E.
PY - 1989
Y1 - 1989
N2 - Six women with a traumatic spinal cord injury (SCI) developed hyperprolactinemia, amenorrhea and galactorrhea. Five of them had thoracic level lesions and 1 had a lumbosacral lesion. Two were postpartum and 1 was pregnant at the time of injury. Transient diabetes insipidus developed in 1 patient. Temporary administration of bromocriptine decreased prolactin levels, caused cessation of lactation and restored ovulatory cycles. The syndrome disappeared spontaneously in all 6 patients. Pituitary stalk concussion resulting from the trauma might cause this phenomenon, with the level of the cord injury playing a role. Being pregnant or early postpartum can predispose women to develop this syndrome.
AB - Six women with a traumatic spinal cord injury (SCI) developed hyperprolactinemia, amenorrhea and galactorrhea. Five of them had thoracic level lesions and 1 had a lumbosacral lesion. Two were postpartum and 1 was pregnant at the time of injury. Transient diabetes insipidus developed in 1 patient. Temporary administration of bromocriptine decreased prolactin levels, caused cessation of lactation and restored ovulatory cycles. The syndrome disappeared spontaneously in all 6 patients. Pituitary stalk concussion resulting from the trauma might cause this phenomenon, with the level of the cord injury playing a role. Being pregnant or early postpartum can predispose women to develop this syndrome.
UR - http://www.scopus.com/inward/record.url?scp=0024456720&partnerID=8YFLogxK
U2 - 10.3109/09513598909152463
DO - 10.3109/09513598909152463
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AN - SCOPUS:0024456720
SN - 0951-3590
VL - 3
SP - 159
EP - 163
JO - Gynecological Endocrinology
JF - Gynecological Endocrinology
IS - 2
ER -
