TY - JOUR
T1 - Hyperglycemia in diabetic patients in general medicine wards
T2 - No independent correlation with in-and out-of-hospital mortality
AU - Buchs, Andreas E.
AU - Braverman, Michal
AU - Rapoport, Micha J.
N1 - Publisher Copyright:
© 2015, Israel Medical Association. All right reserved.
PY - 2015/7/1
Y1 - 2015/7/1
N2 - Background: Admission glucose levels correlate with clinical outcome in patients with type 2 diabetes mellitus (T2DM) hospitalized in general medicine wards. Objective: To investigate whether in-hospital hyperglycemia alone, and after adjustment for age, gender and lipidemia, correlates with in-and out-of-hospital mortality. Methods: Capillary glucose, serum lipids and diagnoses at discharge among patients with T2DM hospitalized in the general medical wards of our hospital were documented. Correlation with in-and out-of-hospital mortality was determined through uni-and multivariate analyses. Results: Of the 4607 patients included in the study 22% died while hospitalized. From a median of five capillary glucose tests obtained per patient, average capillary glucose level was significantly lower in those who survived than in those who died (174 } 64 vs. 180 } 65 mg/dl, P = 0.005). Overall, blood cholesterol was higher in those who survived than in those who died (P < 0.001). Multivariate analysis, however, including age, gender, lipidemia and glycemia, showed that only age and male gender correlated with mortality. Conclusions: Hyperglycemia was associated with increased inand out-of-hospital mortality on univariate analysis. However, it was not an independent risk factor when corrected for age, gender and hyperlipidemia.
AB - Background: Admission glucose levels correlate with clinical outcome in patients with type 2 diabetes mellitus (T2DM) hospitalized in general medicine wards. Objective: To investigate whether in-hospital hyperglycemia alone, and after adjustment for age, gender and lipidemia, correlates with in-and out-of-hospital mortality. Methods: Capillary glucose, serum lipids and diagnoses at discharge among patients with T2DM hospitalized in the general medical wards of our hospital were documented. Correlation with in-and out-of-hospital mortality was determined through uni-and multivariate analyses. Results: Of the 4607 patients included in the study 22% died while hospitalized. From a median of five capillary glucose tests obtained per patient, average capillary glucose level was significantly lower in those who survived than in those who died (174 } 64 vs. 180 } 65 mg/dl, P = 0.005). Overall, blood cholesterol was higher in those who survived than in those who died (P < 0.001). Multivariate analysis, however, including age, gender, lipidemia and glycemia, showed that only age and male gender correlated with mortality. Conclusions: Hyperglycemia was associated with increased inand out-of-hospital mortality on univariate analysis. However, it was not an independent risk factor when corrected for age, gender and hyperlipidemia.
KW - Glucometrics
KW - Hospitalization
KW - Hyperglycemia
KW - Lipids
KW - Mortality
KW - Type 2 diabetes mellitus (T2DM)
UR - http://www.scopus.com/inward/record.url?scp=84937932484&partnerID=8YFLogxK
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C2 - 26357718
AN - SCOPUS:84937932484
SN - 1565-1088
VL - 17
SP - 425
EP - 429
JO - Israel Medical Association Journal
JF - Israel Medical Association Journal
IS - 7
ER -