Hyperbaric oxygen therapy for radiation-induced haemorrhagic cystitis

Amos Neheman*, Ofer Nativ, Boaz Moskovitz, Yehuda Melamed, Avi Stein

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review


OBJECTIVE: To assess the efficacy of hyperbaric oxygen (HBO) for treating haemorrhagic cystitis. PATIENTS AND METHODS: From February 1997 to April 2004, seven patients with radiation-induced haemorrhagic cystitis were treated with HBO; they received a mean (range) of 30 (18-57) HBO treatments and the follow-up was 24 (3-53) months. RESULTS: The haematuria resolved completely in all seven patients shortly after treatment; one had an improvement but died from complications relating to cancer shortly after completing treatment, and two had recurrence of gross haematuria. They were retreated with HBO until the haematuria resolved. CONCLUSIONS: Radiation-induced haemorrhagic cystitis can be treated successfully with HBO primarily or after failure of standard regimens. This method was well tolerated even in patients debilitated by advanced cancer and blood loss. Long-term remission is possible in most patients, and re-treatment effectively manages recurrent bleeding.

Original languageEnglish
Pages (from-to)107-109
Number of pages3
JournalBJU International
Issue number1
StatePublished - Jul 2005
Externally publishedYes


  • Hemorrhagic cystitis
  • Hyperbaric oxygen therapy
  • Radiation therapy


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