Hyperacute renal failure as the initial presentation of systemic lupus erythematosus

O. Arbel, G. Pizov, A. Ben-Yehuda, A. Rubinow, Y. Naparstek, Howard Amital*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review


SLE nephritis is usually a slow process that may lead to renal failure many years after its first presentation. Success of different therapeutic modalities in preventing renal failure is therefore evaluated and compared only after many years of treatment. Lately, this conservative philosophy has been challenged with the acknowledgment of collapsing glomerulopathy (CG), a recent recognized clinical-pathological entity, characterized by rapidly progressive renal failure. Despite this ominous description we present an unusual case of a patient who presented with systemic lupus erythematosus (SLE) and clinical and pathological findings of CG, who completely remitted several weeks after commencing immunosuppressive therapy with intravenous cyclophosphamide and prednisolone.

Original languageEnglish
Pages (from-to)331-333
Number of pages3
Issue number4
StatePublished - 2005
Externally publishedYes


  • Acute renal failure
  • Collapsing glomerulopathy
  • Cyclophosphamide
  • Nephritic syndrome
  • Systemic lupus nephritis


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