Human sperm penetration into cervical mucus in vitro: Correlation between its quality, penetration capacity and velocity

A. Amit, A. Bergman, G. Yedwab, M. P. David, T. Z. Homonnai, G. Paz*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

Abstract

In vitro penetration tests of human sperm into cervical mucus were introduced in order to study the interaction between sperm and cervical mucus. In the present study the correlation between sperm velocity and penetration value has been assessed. 197 semen samples were run in the in vitro penetration test using semen of different qualities and cervical mucus of good quality. No differences were found either between sperm velocity in cervical mucus (17.3 ± 0.9 μm/s) and in semen (19.9 ± 0.8 μm/s) or at different distances measured along the flat capillary tube (1, 2 and 3 cm). A highly significant correlation was found between sperm velocity and penetration value rates (p < 0.0001, r = 0.9). Thus, sperm velocity in semen is a variable of great importance in the assessment of the quality of the ejaculate.

Original languageEnglish
Pages (from-to)283-291
Number of pages9
JournalGynecologic and Obstetric Investigation
Volume14
Issue number4
DOIs
StatePublished - 1982
Externally publishedYes

Keywords

  • Cervical mucus
  • Sperm penetration
  • Sperm quality
  • Sperm velocity

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