Human mitochondrial DNA types in two Israeli populations. A comparative study at the DNA level

B. Bonne-Tamir, M. J. Johnson, A. Natali, D. C. Wallace, L. L. Cavalli-Sforza

Research output: Contribution to journalArticlepeer-review

Abstract

Variations in human mtDNA restriction endonuclease fragment patterns were investigated in a sample number of 81 Israelis - Jews and Arabs - using total blood cell DNA. Eight new morphs were observed using five enzymes: HpaI, BamHI, HaeII, MspI, and AvaII. Of the 18 different combinations of fragment patterns (mtDNA types), only three were shared by both groups, but with striking frequency differences. The Arab sample disclosed 'African' characteristics and was found to be slightly more polymorphic than the Israeli sample. One of the new types filled a 'missing link' originally postulated in a phylogeny of mtDNA human types.

Original languageEnglish
Pages (from-to)341-351
Number of pages11
JournalAmerican Journal of Human Genetics
Volume38
Issue number3
StatePublished - 1986

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