Human chorionic gonadotropin(β-Subunit) in the early diagnosis of ectopic pregnancy

In 15 women with suspected ectopic pregnancy considerable amounts of β-subunit of human chorionic gonadotropin (hCG) were detected in the scrum by the radioimmunoassay technique. The diagnosis was proved by laparotomy. In another 25 suspected cases β-hCG values were less than 1 mlU/ml, and in those cases the diagnosis was excluded. The detection of the (1-subunit of hCG in the serum was found to be an excellent tool for the early diagnosis of ectopic pregnancy, thus helping to prevent the dangerous sequelae which follow in the late diagnosis of this condition. The advantage of detecting the β-subunit of hCG rather than hCG is discussed.