How should a nonfunctioning pituitary macroadenoma be monitored after debulking surgery?

Yona Greenman, Naftali Stern

Research output: Contribution to journalArticlepeer-review

Abstract

Transsphenoidal surgery is the treatment of choice for nonfunctioning pituitary macroadenomas but is seldom curative. Tumour progression rates are high in patients with postoperative remnants. Therefore, long-term monitoring is necessary to detect tumour growth, which may be asymptomatic or manifest with visual field defects and/or pituitary dysfunction. In view of the generally slow-growing nature of these tumours, yearly magnetic resonance imaging, neuro-ophalmologic and pituitary function evaluation are appropriate during the first 3-5 years after surgery. If there is no evidence for tumour progression during this period, testing intervals may be extended thereafter.

Original languageEnglish
Pages (from-to)829-832
Number of pages4
JournalClinical Endocrinology
Volume70
Issue number6
DOIs
StatePublished - Jun 2009

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