Host-Viral Infection Maps Reveal Signatures of Severe COVID-19 Patients

Pierre Bost, Amir Giladi, Yang Liu, Yanis Bendjelal, Gang Xu, Eyal David, Ronnie Blecher-Gonen, Merav Cohen, Chiara Medaglia, Hanjie Li, Aleksandra Deczkowska, Shuye Zhang, Benno Schwikowski, Zheng Zhang, Ido Amit

Research output: Contribution to journalArticlepeer-review

Abstract

A computational framework that allows for the identification and characterization of virus-infected cells as well as bystander cell responses reveals how SARS-CoV-2 alters the immune responses of patients.

Original languageEnglish
Pages (from-to)1475-1488.e12
JournalCell
Volume181
Issue number7
DOIs
StatePublished - 25 Jun 2020
Externally publishedYes

Keywords

  • COVID-19
  • Viral-Track
  • single-cell RNA-seq
  • virus host interactions

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