TY - JOUR
T1 - Host range and oncogenicity studies of the murine myeloma MOPC‐315 type‐C retrovirus
AU - Gazit, Arnona
AU - Guthmann, Daphna
AU - Yaniv, Abraham
PY - 1981/3/15
Y1 - 1981/3/15
N2 - The biological features of an endogenous type‐C RNA tumor virus released by the murine plasmacytoma MOPC‐315 were determined. The virus was found to be pure ecotropic and, according to its capability to infect both NIH/3T3 and BALB/3T3 cells, it was established as an NB tropic virus. This tropism became more pronounced as a consequence of multiple passages in BALB/3T3 cells. In view of the ability of myeloma viruses to efficiently infect BALB/c cells, their possible role in myeloma induction is considered.
AB - The biological features of an endogenous type‐C RNA tumor virus released by the murine plasmacytoma MOPC‐315 were determined. The virus was found to be pure ecotropic and, according to its capability to infect both NIH/3T3 and BALB/3T3 cells, it was established as an NB tropic virus. This tropism became more pronounced as a consequence of multiple passages in BALB/3T3 cells. In view of the ability of myeloma viruses to efficiently infect BALB/c cells, their possible role in myeloma induction is considered.
UR - http://www.scopus.com/inward/record.url?scp=0019507612&partnerID=8YFLogxK
U2 - 10.1002/ijc.2910270312
DO - 10.1002/ijc.2910270312
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C2 - 6270016
AN - SCOPUS:0019507612
SN - 0020-7136
VL - 27
SP - 335
EP - 340
JO - International Journal of Cancer
JF - International Journal of Cancer
IS - 3
ER -
