TY - JOUR
T1 - Home base behavior in amphetamine-treated tame wild rats (Rattus norvegicus)
AU - Eilam, D.
AU - Golani, I.
N1 - Funding Information:
We thank Mr. U. Marder and the staff of the Canadian Center for Ecological Zoology, Tel-Aviv University, for their help in keeping the animals. We also Thank Drs. H. Szechtman and R. Schuster for critical comments. This study was supported by the Israel Institute for Psychobiology, Charles E. Smith Foundation, Grant 6-87-8.
PY - 1990/1/1
Y1 - 1990/1/1
N2 - When a rat treated with amphetamine (0.5-5 mg/kg) locomotes in an unfamiliar environment, there are one or two places which it visits most often. In these one or two places the mean duration of a visit (stop) is the longest, and, compared to other places, the incidence of grooming and rearing are the highest. Since in intact rats these features of place characterize it as a 'home base', it is concluded that under amphetamine rats also establish one or two home bases. One home base was generally established by rats treated with low doses of amphetamine, while two bases were most evident in those treated with high doses. Since the paths of locomotion in amphetamine-treated rats were previously described to be stereotyped, it is suggested that home base location under this drug may be used as a reference point in the assessment of the organization of stereotyped locomotor behavior.
AB - When a rat treated with amphetamine (0.5-5 mg/kg) locomotes in an unfamiliar environment, there are one or two places which it visits most often. In these one or two places the mean duration of a visit (stop) is the longest, and, compared to other places, the incidence of grooming and rearing are the highest. Since in intact rats these features of place characterize it as a 'home base', it is concluded that under amphetamine rats also establish one or two home bases. One home base was generally established by rats treated with low doses of amphetamine, while two bases were most evident in those treated with high doses. Since the paths of locomotion in amphetamine-treated rats were previously described to be stereotyped, it is suggested that home base location under this drug may be used as a reference point in the assessment of the organization of stereotyped locomotor behavior.
KW - (+)-Amphetamine
KW - Cognitive map
KW - Exploration
KW - Grooming
KW - Open field
KW - Spatial memory, Locomotion
KW - Stopping
UR - http://www.scopus.com/inward/record.url?scp=0025062629&partnerID=8YFLogxK
U2 - 10.1016/0166-4328(90)90170-J
DO - 10.1016/0166-4328(90)90170-J
M3 - ???researchoutput.researchoutputtypes.contributiontojournal.article???
AN - SCOPUS:0025062629
VL - 36
SP - 161
EP - 170
JO - Behavioural Brain Research
JF - Behavioural Brain Research
SN - 0166-4328
IS - 1-2
ER -