HLA Polymorphism in Israel: 3. Ashkenazi Jews of German Descent

B. Bonné‐Tamir*, J. G. Bodmer, J. Modai

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review


Seventy‐three random Jewish individuals whose families have lived in Germany for at least 4–5 generations, were typed for HLA antigens at the A and B loci. In comparison with other European populations, the frequencies of B7 and B12 are low whereas Bw35 is almost twice as frequent (21%). Among the uncommon associations found in the German Jews were: (A2, Bw21), (Aw25, B18), (A29, B14), (A28, Bw15). The frequent haplotype (Aw24, Bw35) was previously found, but only in Asia and in American Indians. Subdivisions of the subjects according to geographic regions within Germany point to differences in gene frequency between the groups.

Original languageEnglish
Pages (from-to)206-212
Number of pages7
JournalTissue Antigens
Issue number3
StatePublished - Mar 1978


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