HIV-1 positive feedback and lytic fate

Iftach Nachman, Sharad Ramanathan

Research output: Contribution to journalShort surveypeer-review

Abstract

The HIV viral lifecycle includes infection of a host cell, followed by a critical decision between latency and lysis. A new study suggests that positive feedback in the HIV-1 promoter, involving Tat protein and gene expression, has a role in this critical choice of fate.

Original languageEnglish
Pages (from-to)382-383
Number of pages2
JournalNature Genetics
Volume40
Issue number4
DOIs
StatePublished - Apr 2008
Externally publishedYes

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