Hyponatremia in refractory congestive heart failure patients treated with icodextrin-based peritoneal dialysis: A case series

Translated title of the contribution: Hyponatremia in refractory congestive heart failure patients treated with icodextrin-based peritoneal dialysis: A case series

Margarita Kunin*, Liat Ganon, Eli J. Holtzman, Dganit Dinour

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

5 Scopus citations

Abstract

Severe congestive heart failure (CHF) patients are prone to hyponatremia. Peritoneal dialysis (PD) is increasingly used for long-term management of refractory CHF patients. The glucose polymer icodextrin was proposed to be a good option for fluid removal in such patients. A small, although statistically significant reduction in serum sodium (∼2 mmol/l) consistently observed in multiple trials, is considered as not clinically relevant. Here we reported five refractory CHF patients who demonstrated sodium drop by median of 8 meq/l (range 5.4–8.3 meq/l) after icodextrin was added to their program. It seems that icodextrin may contribute to clinically relevant hyponatremia if the hyponatremia is compounded by other factors. Patients with extremely severe congestive heart failure are susceptible to this complication.

Translated title of the contributionHyponatremia in refractory congestive heart failure patients treated with icodextrin-based peritoneal dialysis: A case series
Original languageEnglish
Pages (from-to)87-91
Number of pages5
JournalNefrologia
Volume38
Issue number1
DOIs
StatePublished - Jan 2018

Keywords

  • Congestive heart failure
  • Hyponatremia
  • Peritoneal dialysis

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