TY - JOUR
T1 - High-resolution STM imaging of novel poly(G)-poly(C) DNA molecules
AU - Shapir, Errez
AU - Cohen, Hezy
AU - Borovok, Natalia
AU - Kotlyar, Alexander B.
AU - Porath, Danny
PY - 2006/3/9
Y1 - 2006/3/9
N2 - High-resolution scanning tunneling microscopy (STM) imaging of single double-stranded poly(G)-poly(C) DNA molecules, made by a novel synthesis method, shows the molecules morphology. The STM images reveal a periodic structure of ∼4 nm, seen as repeating "bulbs" along the molecules. These "bulbs" are associated with the molecule helix (the major grooves). "Nicks", two per 100 nm on the average, are observed along the DNA as well. The STM measurements were supported by a morphological statistics of the DNA molecule groove length and apparent height relative to the surface.
AB - High-resolution scanning tunneling microscopy (STM) imaging of single double-stranded poly(G)-poly(C) DNA molecules, made by a novel synthesis method, shows the molecules morphology. The STM images reveal a periodic structure of ∼4 nm, seen as repeating "bulbs" along the molecules. These "bulbs" are associated with the molecule helix (the major grooves). "Nicks", two per 100 nm on the average, are observed along the DNA as well. The STM measurements were supported by a morphological statistics of the DNA molecule groove length and apparent height relative to the surface.
UR - http://www.scopus.com/inward/record.url?scp=33645653337&partnerID=8YFLogxK
U2 - 10.1021/jp0569638
DO - 10.1021/jp0569638
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C2 - 16509745
AN - SCOPUS:33645653337
SN - 1520-6106
VL - 110
SP - 4430
EP - 4433
JO - Journal of Physical Chemistry B
JF - Journal of Physical Chemistry B
IS - 9
ER -