High rate of vaginal infections caused by non-C. albicans Candida species among asymptomatic women

Michael Dan, F. Poch, D. Levin

Research output: Contribution to journalArticlepeer-review

Abstract

A prospective observational study of patients attending a gynecological clinic and those referred to a clinic for genitourinary infections was undertaken with the purpose of evaluating the relative prevalence of non-C. albicans Candida species among Candida isolates from the vagina in different clinical settings in an area with high occurrence of vulvovaginal candidiasis. The rate of non-C. albicans Candida species was 44.5% among asymptomatic women, 19.4% among those with sporadic vaginitis and 21% among patients with chronic vaginal symptoms (p<0.001 for asymptomatic vs. pooled symptomatic women). No increase in the rate of non-C. albicans Candida was observed during a period of 4 years (1995-1998) despite a 1.57-fold increase in the sales of azole antifungal agents. Unlike some previous reports we could not document an association of non-C. albicans Candida species with chronic vaginal symptoms or increased use of azole antifungal agents. The significant higher rate of these yeasts in asymptomatic women is in accord with the known tendency of non-C. albicans Candida species to cause mild symptoms.

Original languageEnglish
Pages (from-to)383-386
Number of pages4
JournalMedical Mycology
Volume40
Issue number4
DOIs
StatePublished - Aug 2002
Externally publishedYes

Keywords

  • Azole antifungal agents
  • Non-C albicans Candida species
  • Vulvovaginal candidiasis

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