@article{54ec31b700834b41b6f7b0727bb52c04,
title = "High frequency of MGUS in DSP",
abstract = "Introduction: Monoclonal gammopathy has been reported in several polyneuropathies. In this study, we sought to explore the frequency and characteristics of monoclonal gammopathy in patients with diabetic sensorimotor polyneuropathy (DSP). Methods: Patients with type 1 and type 2 diabetes mellitus (DM 1, DM 2) and controls without diabetes were evaluated between November 2008 and December 2013. Results: Fifty controls, 66 patients with DM 1, and 106 patients with DM 2 were included, with average ages of 43 ± 18, 45 ± 17, and 65 ± 10 years, respectively; the frequency of monoclonal gammopathy was 0%, 8%, and 15%, respectively. In patients with DSP, the frequency of monoclonal gammopathy increased to 14% in DM 1 and 21% in DM 2; the most common monoclonal proteins were immunoglobulin (Ig) M and IgG, respectively. Discussion: DSP might be associated with a high frequency of monoclonal gammopathy, with different characteristics in DM 1 and in DM 2. Muscle Nerve 57: 1018–1021, 2018.",
keywords = "HbA1c, diabetic polyneuropathy, monoclonal gammopathy, sural nerve action potential amplitude, type 1 DM, type 2 DM",
author = "Alon Abraham and Carolina Barnett and Katzberg, {Hans D.} and Lovblom, {Leif E.} and Perkins, {Bruce A.} and Vera Bril",
note = "Publisher Copyright: {\textcopyright} 2018 Wiley Periodicals, Inc.",
year = "2018",
month = jun,
doi = "10.1002/mus.26054",
language = "אנגלית",
volume = "57",
pages = "1018--1021",
journal = "Muscle and Nerve",
issn = "0148-639X",
publisher = "John Wiley & Sons Inc.",
number = "6",
}
