TY - JOUR
T1 - High blood pressure variability predicts 30-day mortality but not 1-year mortality in hospitalized elderly patients
AU - Weiss, Avraham
AU - Rudman, Yaron
AU - Beloosesky, Yichayaou
AU - Akirov, Amit
AU - Shochat, Tzippy
AU - Grossman, Alon
N1 - Publisher Copyright:
© 2017 Informa UK Limited, trading as Taylor & Francis Group.
PY - 2017/9/3
Y1 - 2017/9/3
N2 - Background: The association of blood pressure (BP) variability (BPV) in hospitalized patients, which represents day-to-day variability, with mortality has been extensively reported in patients with stroke, but poorly defined for other medical conditions. Aim and method: To assess the association of day-to-day blood pressure variability in hospitalized patients, 10 BP measurements were obtained in individuals ≥75 years old hospitalized in a geriatric ward. Day-to-day BPV, measured 3 times a day, was calculated in each patient as the coefficient of variation of systolic BP. Patients were stratified by quartiles of coefficient of variation of systolic BP, and 30-day and 1-year mortality data were compared between those in the highest versus the lowest (reference) group. Results: Overall, 469 patients were included in the final analysis. Mean coefficient of variation of systolic BP was 12.1%. 30-day mortality and 1-year mortality occurred in 29/469 (6.2%) and 95/469 (20.2%) individuals respectively. Patients in the highest quartile of BPV were at a significantly higher risk for 30-day mortality (HR =4.12, CI 1.12–15.10) but not for 1-year mortality compared with the lowest BPV quartile (HR =1.61, CI 0.81–3.23). Conclusions: Day-to-day BPV is associated with 30-day, but not with 1-year mortality in hospitalized elderly patients.
AB - Background: The association of blood pressure (BP) variability (BPV) in hospitalized patients, which represents day-to-day variability, with mortality has been extensively reported in patients with stroke, but poorly defined for other medical conditions. Aim and method: To assess the association of day-to-day blood pressure variability in hospitalized patients, 10 BP measurements were obtained in individuals ≥75 years old hospitalized in a geriatric ward. Day-to-day BPV, measured 3 times a day, was calculated in each patient as the coefficient of variation of systolic BP. Patients were stratified by quartiles of coefficient of variation of systolic BP, and 30-day and 1-year mortality data were compared between those in the highest versus the lowest (reference) group. Results: Overall, 469 patients were included in the final analysis. Mean coefficient of variation of systolic BP was 12.1%. 30-day mortality and 1-year mortality occurred in 29/469 (6.2%) and 95/469 (20.2%) individuals respectively. Patients in the highest quartile of BPV were at a significantly higher risk for 30-day mortality (HR =4.12, CI 1.12–15.10) but not for 1-year mortality compared with the lowest BPV quartile (HR =1.61, CI 0.81–3.23). Conclusions: Day-to-day BPV is associated with 30-day, but not with 1-year mortality in hospitalized elderly patients.
KW - Blood pressure
KW - elderly
KW - mortality
KW - variability
UR - http://www.scopus.com/inward/record.url?scp=85014627694&partnerID=8YFLogxK
U2 - 10.1080/08037051.2017.1300859
DO - 10.1080/08037051.2017.1300859
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C2 - 28270031
AN - SCOPUS:85014627694
SN - 0803-7051
VL - 26
SP - 259
EP - 263
JO - Blood Pressure
JF - Blood Pressure
IS - 5
ER -