Abstract
Background: The association of blood pressure (BP) variability (BPV) in hospitalized patients, which represents day-to-day variability, with mortality has been extensively reported in patients with stroke, but poorly defined for other medical conditions. Aim and method: To assess the association of day-to-day blood pressure variability in hospitalized patients, 10 BP measurements were obtained in individuals ≥75 years old hospitalized in a geriatric ward. Day-to-day BPV, measured 3 times a day, was calculated in each patient as the coefficient of variation of systolic BP. Patients were stratified by quartiles of coefficient of variation of systolic BP, and 30-day and 1-year mortality data were compared between those in the highest versus the lowest (reference) group. Results: Overall, 469 patients were included in the final analysis. Mean coefficient of variation of systolic BP was 12.1%. 30-day mortality and 1-year mortality occurred in 29/469 (6.2%) and 95/469 (20.2%) individuals respectively. Patients in the highest quartile of BPV were at a significantly higher risk for 30-day mortality (HR =4.12, CI 1.12–15.10) but not for 1-year mortality compared with the lowest BPV quartile (HR =1.61, CI 0.81–3.23). Conclusions: Day-to-day BPV is associated with 30-day, but not with 1-year mortality in hospitalized elderly patients.
Original language | English |
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Pages (from-to) | 259-263 |
Number of pages | 5 |
Journal | Blood Pressure |
Volume | 26 |
Issue number | 5 |
DOIs | |
State | Published - 3 Sep 2017 |
Keywords
- Blood pressure
- elderly
- mortality
- variability