TY - JOUR
T1 - Heterotopic ossification in Guillain-Barré syndrome
T2 - Incidence and effects on functional outcome with long-term follow-up
AU - Zeilig, Gabi
AU - Weingarden, Harold P.
AU - Levy, Richard
AU - Peer, Inbal
AU - Ohry, Avi
AU - Blumen, Nava
PY - 2006/1
Y1 - 2006/1
N2 - Objective: To define the incidence, effects on functional abilities, and possible causation of heterotopic ossification (HO) in Guillain-Barré syndrome (GBS) patients admitted for inpatient rehabilitation. Design: Long-term prospective study on neurologic and functional outcome of GBS patients admitted for rehabilitation. Setting: Rehabilitation department, inpatient and outpatient, within a university-affiliated medical center. Participants: All GBS patients admitted for rehabilitation and followed for a minimum of 3 years. Interventions: Not applicable. Main Outcome Measures: Presence of HO, factors that may be etiologically significant, and effects on functionality. Data included: medical interventions, Disability Grading Scale, need for assisted ventilation, electrodiagnostic findings, autonomic function, standard neuro-musculo-skeletal evaluation, and hospital length of stay. Results: Four (6%) of 65 patients had HO, 24 of whom required mechanical ventilation. All had decreased range of motion in the involved hips that affected mobility. Conclusions: Even though it has been rarely reported, HO does occur in GBS and affects functional outcome.
AB - Objective: To define the incidence, effects on functional abilities, and possible causation of heterotopic ossification (HO) in Guillain-Barré syndrome (GBS) patients admitted for inpatient rehabilitation. Design: Long-term prospective study on neurologic and functional outcome of GBS patients admitted for rehabilitation. Setting: Rehabilitation department, inpatient and outpatient, within a university-affiliated medical center. Participants: All GBS patients admitted for rehabilitation and followed for a minimum of 3 years. Interventions: Not applicable. Main Outcome Measures: Presence of HO, factors that may be etiologically significant, and effects on functionality. Data included: medical interventions, Disability Grading Scale, need for assisted ventilation, electrodiagnostic findings, autonomic function, standard neuro-musculo-skeletal evaluation, and hospital length of stay. Results: Four (6%) of 65 patients had HO, 24 of whom required mechanical ventilation. All had decreased range of motion in the involved hips that affected mobility. Conclusions: Even though it has been rarely reported, HO does occur in GBS and affects functional outcome.
KW - Guillain-Barré syndrome
KW - Ossification, heterotopic
KW - Rehabilitation
KW - Treatment outcome
UR - http://www.scopus.com/inward/record.url?scp=30144439909&partnerID=8YFLogxK
U2 - 10.1016/j.apmr.2005.07.308
DO - 10.1016/j.apmr.2005.07.308
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C2 - 16401445
AN - SCOPUS:30144439909
SN - 0003-9993
VL - 87
SP - 92
EP - 95
JO - Archives of Physical Medicine and Rehabilitation
JF - Archives of Physical Medicine and Rehabilitation
IS - 1
ER -