Heterogeneity in dementia: Challenges and opportunities

Jiska Cohen-Mansfield*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

48 Scopus citations


The major sources of heterogeneity in the manifestation of dementia are analyzed as stemming from three types of sources: initial predisposing factors, lifelong events, and the current condition. Each of these sources is, in turn, comprised of three general domains: genetic/biologic/medical, psychosocial, and environmental. These influences affect the manifestation of dementia in terms of cognitive, behavioral, self-maintenance, and affective functioning. Mapping the sources and manifestations of this heterogeneity can lead to both a more thorough understanding of people with dementia and the development of management settings and interventions that are more responsive to people with dementia.

Original languageEnglish
Pages (from-to)60-63
Number of pages4
JournalAlzheimer Disease and Associated Disorders
Issue number2
StatePublished - Apr 2000
Externally publishedYes


  • Diversity
  • Heterogeneity
  • Individualization


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