TY - JOUR
T1 - Hepatitis in an infant treated with octreotide for congenital hyperinsulinism
AU - Koren, Ilana
AU - Riskin, Arieh
AU - Barthlen, Winfried
AU - Gillis, David
PY - 2013/2
Y1 - 2013/2
N2 - Congenital hyperinsulinism is characterized by hypoglycemia caused by several genetic disorders of inappropriate insulin secretion. Octreotide, an analogue of somatostatin, plays a major role in the pharmaceutical treatment of this condition. A 9-month-old infant treated with octreotide developed anicteric hepatitis with no other proven cause. After the discontinuation of this drug, the liver enzymes declined rapidly. Liver function tests should be followed in patients receiving octreotide.
AB - Congenital hyperinsulinism is characterized by hypoglycemia caused by several genetic disorders of inappropriate insulin secretion. Octreotide, an analogue of somatostatin, plays a major role in the pharmaceutical treatment of this condition. A 9-month-old infant treated with octreotide developed anicteric hepatitis with no other proven cause. After the discontinuation of this drug, the liver enzymes declined rapidly. Liver function tests should be followed in patients receiving octreotide.
KW - Congenital hyperinsulinism
UR - http://www.scopus.com/inward/record.url?scp=84878293101&partnerID=8YFLogxK
U2 - 10.1515/jpem-2012-0372
DO - 10.1515/jpem-2012-0372
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C2 - 23327817
AN - SCOPUS:84878293101
SN - 0334-018X
VL - 26
SP - 183
EP - 185
JO - Journal of Pediatric Endocrinology and Metabolism
JF - Journal of Pediatric Endocrinology and Metabolism
IS - 1-2
ER -
