Hepatitis E virus infection in travelers

Eli Schwartz, Nancy Piper Jenks, Pierre Van Damme, Eithan Galun

Research output: Contribution to journalArticlepeer-review


Hepatitis E virus (HEV) is a major cause of clinical hepatitis in regions of endemicity, affecting primarily young adults and travelers to these areas. We present 5 cases of acute HEV infection in travelers and review 143 cases of HEV infection found by a literature search that were contracted in areas of endemicity. Fulminant hepatitis occurred in 2.7% of the reported cases; 2 of these were fatal. The destination of most of the travelers with acute HEV infection was the Indian subcontinent. The overall risk of contracting HEV infection for travelers appears to be lower than the risk for hepatitis A virus infection. Pregnant women and individuals with underlying liver disease may be a risk for severe infection.

Original languageEnglish
Pages (from-to)1312-1314
Number of pages3
JournalClinical Infectious Diseases
Issue number5
StatePublished - 1999


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