Hepatitis E Virus genotype 3 in Sewage and Genotype 1 in Acute Hepatitis Cases, Israel

Daniela Ram, Yossi Manor, Yael Gozlan, Eli Schwartz, Ziv Ben-Ari, Ella Mendelson, Orna Mor*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

Abstract

Hepatitis E virus (HEV) is an emerging infectious agent in developed countries. HEV genotypes 1 (G1) and 3 (G3) have been identified in environmental and clinical samples in Europe. In Israel, the overall prevalence of anti-HEV IgG antibodies was found to be 10.6%; however, reports of HEV infection are scarce. In this study, the presence of HEV in Israel was investigated using 169 sewage samples from 32 treatment facilities and 49 samples from acute hepatitis patients, all collected between 2013 and 2015. Fourteen sewage samples, from Haifa (11/18 samples), Tel Aviv (2/29 samples), and Beer Sheva (1/17 samples), regions with good sanitary conditions and middle-high socio economic populations, were HEV positive. Among the patient samples, 6.1% (3/49) were HEV positive, all returning travelers from India. Genotype analysis revealed G1 HEV in patients and G3 HEV sequences in sewage. Evidence that HEV could be establishing itself in our region may justify more active surveillance to monitor its spread.

Original languageEnglish
Pages (from-to)216-220
Number of pages5
JournalAmerican Journal of Tropical Medicine and Hygiene
Volume95
Issue number1
DOIs
StatePublished - Jul 2016

Fingerprint

Dive into the research topics of 'Hepatitis E Virus genotype 3 in Sewage and Genotype 1 in Acute Hepatitis Cases, Israel'. Together they form a unique fingerprint.

Cite this