Hepatic artery thrombosis in pediatric liver transplantation: Graft salvage after thrombectomy

R. Garcia-Gallont, N. Bar-Nathan, E. Shaharabani, A. Yussim, R. Shapira, I. Zahavi, Z. Shapira, G. Dinari, E. Mor*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review


Hepatic artery thrombosis (HAT) is a devastating complication that may occur after orthotopic liver transplantation (OLT). A higher incidence has been reported in children. Salvage of the graft by thrombectomy has been suggested as an alternative to re-transplantation. In this study we report the outcome of three children who underwent thrombectomy for HAT. Between January 1992 and June 1998, 14 children (< 17 yrs of age) underwent liver transplantation. Three developed HAT (one a whole-liver graft recipient, age 17; two living-related graft recipients, ages 4 and 4.5 yr). In the first patient, thrombosis of the hepatic artery was associated with scattered areas of parenchymal necrosis on computed tomography. In the two living-related patients, HAT was found incidentally during re-exploration for bleeding (day 2 and day 10). Thrombectomy was performed in all three patients. At 18-24 months after thrombectomy, all three children had normal graft function. In the first patient, complete regeneration of the liver has been documented by computed tomography and a late asymptomatic recurrent thrombosis is suggested by absence of arterial flow on Doppler examination. The hepatic artery is patent in the two living-related recipients. One of these living-related recipients developed ischemic bile duct stricture and underwent successful percutaneous balloon dilatation. We conclude that long-term normal graft function can be achieved by thrombectomy in pediatric liver recipients with HAT, even in the presence of limited parenchymal damage.

Original languageEnglish
Pages (from-to)74-78
Number of pages5
JournalPediatric Transplantation
Issue number1
StatePublished - Feb 1999
Externally publishedYes


  • Children
  • Hepatic artery
  • Liver transplantation
  • Thrombosis


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