Hepatic and splenic sarcoidosis: Ultrasound and MR imaging

Ada Kessler, Donald G. Mitchell, Harold L. Israel, Barry B. Goldberg

Research output: Contribution to journalArticlepeer-review

Abstract

Abdominal imaging studies may be performed for various indications in patients known to have sarcoidosis. To assess magnetic resonance imaging (MRI) and sonographic ability to detect abnormalities in sarcoidosis patients with abdominal involvement, a prospective study on 18 selected patients was performed. Besides organomegaly, when present, ultrasound demonstrated normal or increased hepatic parenchymal echogenicity, coarsening of the liver parenchyma with or without discrete nodules, focal calcifications, as well as contour irregularity. Splenic discrete nodules were seen on ultrasound in a single patient. Besides organomegaly, MRI abnormalities include abnormal hepatic signal intensity, discrete nodules, contour irregularity, spiculation of small hepatic vascular branches, and a high periportal signal intensity. MRI splenic abnormalities include contour irregularity, nodularity, and abnormal signal intensity. The data presented in this study reveals the spectrum of ultrasound and MRI findings in sarcoidosis patients with abdominal organ involvement, potentially enabling the evaluation of the severity of the disease. MRI appears more sensitive than ultrasound for study of abdominal sarcoidosis.

Original languageEnglish
Pages (from-to)159-163
Number of pages5
JournalAbdominal Imaging
Volume18
Issue number2
DOIs
StatePublished - Jun 1993
Externally publishedYes

Keywords

  • Abdomen, US and MRI
  • Sarcoidosis, liver involvement
  • Splenomegaly, diagnosis

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