Heparin-induced thrombocytopenia as an autoimmune disease - Idiotypic evidence for the role of anti-heparin/PF4 autoantibodies

Y. Shoenfeld

Heparin-induced thrombocytopenia as an autoimmune disease - Idiotypic evidence for the role of anti-heparin/PF4 autoantibodies

Y. Shoenfeld^*

^*Corresponding author for this work

Sheba Medical Center at Tel Hashomer

Research output: Contribution to journal › Short survey › peer-review

4 Scopus citations

Abstract

The results of this study support the importance of anti-PF4/heparin antibodies in the parthogenesis of HIT. The induction of mouse anti-PF4/heparin and thrombocytopenia upon exposure to heparin can provide a means to evaluate new therapeutic modalities for immunoregulation of anti-PF4/heparin expression.

Original language	English
Pages (from-to)	243-245
Number of pages	3
Journal	Israel Journal of Medical Sciences
Volume	33
Issue number	4
State	Published - Apr 1997
Externally published	Yes

Keywords

Heparin
Platelet factor-4
Thrombocytopenia

Cite this

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title = "Heparin-induced thrombocytopenia as an autoimmune disease - Idiotypic evidence for the role of anti-heparin/PF4 autoantibodies",

abstract = "The results of this study support the importance of anti-PF4/heparin antibodies in the parthogenesis of HIT. The induction of mouse anti-PF4/heparin and thrombocytopenia upon exposure to heparin can provide a means to evaluate new therapeutic modalities for immunoregulation of anti-PF4/heparin expression.",

keywords = "Heparin, Platelet factor-4, Thrombocytopenia",

author = "Y. Shoenfeld",

year = "1997",

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language = "אנגלית",

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N2 - The results of this study support the importance of anti-PF4/heparin antibodies in the parthogenesis of HIT. The induction of mouse anti-PF4/heparin and thrombocytopenia upon exposure to heparin can provide a means to evaluate new therapeutic modalities for immunoregulation of anti-PF4/heparin expression.

AB - The results of this study support the importance of anti-PF4/heparin antibodies in the parthogenesis of HIT. The induction of mouse anti-PF4/heparin and thrombocytopenia upon exposure to heparin can provide a means to evaluate new therapeutic modalities for immunoregulation of anti-PF4/heparin expression.

KW - Heparin

KW - Platelet factor-4

KW - Thrombocytopenia

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JO - Israel Journal of Medical Sciences

JF - Israel Journal of Medical Sciences

IS - 4

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Heparin-induced thrombocytopenia as an autoimmune disease - Idiotypic evidence for the role of anti-heparin/PF4 autoantibodies

Abstract

Keywords

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