Heparin-induced thrombocytopenia (HIT) is an immunemediated coagulation side effect of heparin therapy characterized by thrombocytopenia and by a paradoxical prothrombotic state following heparin exposure when thrombotic or thromboembolic events accurse, the condition is classified as Heparin-induced thrombocytopenia with thrombosis (HITT). We report a case of HITT with evidence of small-vessel arterial thrombosis in a 5-day-old newborn receiving extracorporeal membrane oxygenation (ECMO) for congenital diaphragmatic hernia, and our attempt of bivalirudin alternative treatment. We also review previous reports regarding HIT and ECMO with the alternative management in this unique population.
|Number of pages||8|
|Journal||Journal of Extra-Corporeal Technology|
|State||Published - Mar 2011|
- Direct thrombin inhibitor
- Extracorporeal membrane oxygenation
- Heparin-induced thrombocytopenia